The house, located in the luxury community of Toluca Lake in Los Angeles, is located behind a wall of gates and is listed for $6.5 million.
Here's an interesting fact about the four-bedroom, 5.5-bathroom, 4,535-square-foot property.
Drew purchased the place from actress Jennifer Love Hewitt for $4.1 million in 2014.
She snagged the residence after splitting from Jessica and Ashlee's father, Joe Simpson.
If she gets the asking price for the house, Drew will be well on his way to making a good profit in the bank.
However, it's hard to leave a house you've lived in for nearly a decade, especially one with such a water view. Here's what she will be leaving behind.
This Mediterranean-style home is 12 miles from downtown Los Angeles and has a beautiful courtyard where outdoor living can be easily imagined.
The home's chic kitchen has a casual yet upscale style thanks to the apron sink and butcher's island.
Hardwood floors and subtle built-ins span three floors, while French doors open from the kitchen and family room to views of the lake from the upper and lower decks.
Upstairs, the main suite has a bespoke wardrobe and dressing area.
At the back of the house, there is a private dock, small pool and cabana, an outdoor kitchen, full bathroom and fitness space.
Jessica Simpson, who is married to former NFL player Eric Johnson, continues to sing, act and keep her fashion line, the Jessica Simpson Collection, wildly successful.
Ashlee Simpson, who is also an entrepreneur, is married to actor and musician Evan Ross, the son of Motown music legend Diana Ross.